Immunology-Level 1

Question 1 of 18

1 point(s)

The following cells are antigen presenting cells EXCEPT

B-lymphocyte
T-lymphocyte
Macrophages
Langerhans' cells
Dendritic cells
Cytotoxic T cells

Question 2 of 18

1 point(s)

Allogeneic antigens are

antigens found within the same individual
antigens found in genetically identical individuals
antigens found in genetically dissimilar members of the same species
antigens found in different species

Question 3 of 18

1 point(s)

A polymorphonuclear neutrophil (PMN):

Is a bone marrow stem cell.
Is closely similar to a mast cell.
Contains microbicidal cytoplasmic granules.
Is not a professional phagocytic cell.
Has granules which stain with eosin.

Question 4 of 18

1 point(s)

Select statements that are true about Haptens

are small organic molecules that are antigenic but not immunogenic by themselves
are small molecules that generate an immune response when they are attached to a large carrier molecule such as a protein
Once the body has generated antibodies to a hapten-carrier adduct, the small-molecule hapten may also be able to bind to the antibody
cannot elicit an antibody response on its own, it can bind with antibodies and act as an antigen
molecules with a molecular weight more than 5,000 KDa

Question 5 of 18

1 point(s)

Acute inflammation characteristically involves:

Constriction of arterioles
Capillary endothelial cell enlargement.
Influx of macrophages.
Influx of mast cells.
Influx of neutrophils

Question 6 of 18

1 point(s)

Hyper-viscosity syndrome is associated with the following

myeloma
Haemangioma
Ehrlichia canis infection
Cat scratch fever

Question 7 of 18

1 point(s)

Hyper-viscosity syndrome associated with myeloma is due to heightened production of

IgM
IgD
IgE
IgG

Question 8 of 18

1 point(s)

Cytokines exhibit these four characteristics

Pleiotropism
Redundancy
Synergism
antagonism
Idiosyncrasy

Question 9 of 18

1 point(s)

The mononuclear phagocyte system does not include:

Monocytes
Endothelial cells
Langerhans cells
Intraglomerular mesangial cells
Kupffer cells

Question 10 of 18

1 point(s)

A cytokine can do all of the following EXCEPT

bind to receptors which do not share cytokine-binding sub units.
bind to its specific receptor on the same cell that produced it.
bind to receptor antagonists produced by pathogenic viruses.
compete with other cytokines whose receptors share signal-transducing subunits
upregulate (increase) synthesis of high affinity subunits for its receptor.

Question 11 of 18

1 point(s)

Which of the following does not protect body surfaces:

Skin
Gastric acid
Mucus
Salivary amylase
Gut microflora

Question 12 of 18

1 point(s)

What are chemokines?

small proteins produced by leukocytes and tissue cells that are involved in migration of leukocytes from blood to tissues and activation of or other leukocytes
proteins that inhibit the biological activity of cytokines; they can bind directly to a cytokine receptor without activating it or can bind directly to a cytokine inhibiting its activity
secreted viral proteins that mimic host cytokines
bind with their respective cytokine preventing the cytokine from interacting with the membrane bound receptor

Question 13 of 18

1 point(s)

Sequentially arrange the steps involved in the microbial phagocytic process?

formation of the residual body with indigestible material
chemotaxis and adherence of the microbe to the phagocyte
discharge of waste
ingestion of the microbe by the phagocyte
formation of the phagosome
formation of the phagolysosome
digestion of ingested microbe by enzymes

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Question 14 of 18

1 point(s)

What do tertiary granules found in neutrophils contain?

Metalloproteinases
Hydrolases
Defensins
Histamine
Serotonin

Question 15 of 18

1 point(s)

Which type of leukocyte represents up to 50% of circulating leukocytes in the blood of a healthy dog?

Eosinophils
Neutrophils
Monocytes
Lymphocytes
Erythrocytes

Question 16 of 18

1 point(s)

What is a disadvantage of administering a modified live vaccine?

Increased chance that the animal can develop the disease after vaccination
Does not require a booster vaccination 3 to 4 weeks after the initial vaccination
Stimulates both antibody production and cell-mediated immunity
Provides a higher level of and longer lasting immunity

Question 17 of 18

1 point(s)

What is the most serious potential side effect of vaccination

Swelling
Bleeding from the site of Injection
Fever
Anaphylaxis

Question 18 of 18

1 point(s)

Which of the following is a circulating blood cell that is capable of differentiating into a plasma cell?

T-lymphocyte
B-lymphocyte
Natural killer cells
Neutrophil
Macrophage
Mast cell

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Immunology-Level 1

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